Pycnogenols are found in a vast array of supplements, including grape seed extract. The major constituents in grape seed and pine bark extracts are proanthocyanidins. Edited November 21, 2011 at 4:16 pm Purpose: To evaluate the efficacy and safety of orally administered grape seed proanthocyanidin extract (GSPE) in patients with non-proliferative diabetic retinopathy (NPDR).. Methods: In this randomized (1:2:2), multicentre, double-blind trial, patients (n = 124; age: 40–78 years) were administered placebo, calcium dobesilate (CD; 750 mg/d), or GSPE (150 mg/d) orally for up to 12 … I don't know if it's still available, but so worth reading and getting on this supp. In addition, people should take Vitamin C in a ratio 10 times higher than the grape seed extract (750 mg/day). There is little to no difference between Pine Bark Extract vs Pycnogenol in terms of composition or effects. Subjects who received 100 to 300 mg of Pycnogenol had the most significant lowering of their fasting glucose levels. Is Pycnogenol the same as Pine Bark Extract? In an open, controlled comparative study 40 patients with diagnosed CVI were treated either with 60 … Some people have replaced their vitamins supplements totally with Pycnogenol®, thinking that it offers better protection. Grapes. It should be understood that any compounds with proanthocyanidins cannot take the place of the other vitamins. In addition to a reduction in the use of NSAIDs, a reduction in the number of painful days due to dysmenorrhea from 2.1 days before supplementation to 1.3 days during the third and fourth menstrual cycle" - See Pycnogenol at Amazon.com or grape seed extract at Amazon.com (some say the grape seed extract is the same without the patent markup). Make sure you always follow the dosage scheme and be aware of the side effects and interaction with other drugs. You may use pine bark extract and either pycnogenol to help treat a variety of medical conditions, including chronic venous insufficiency, retinopathy or erectile dysfunction. Q: Grape seed extract vs Pycnogenol: what’s the difference? Horphag would have you believe all the health benefits from OPC are exclusive to pine bark extract (pycnogenol), however the bulk of research originating out of France from roughly 1950 to 1980 was done with grape seed extract. Thus a 100 mg serving would contain 65 to 75 mg of proanthocyanidins (procyanidins). Pycnogenol and Grape Seed Extract is a potent combination of two powerful natural antioxidants - Pycnogenol, extracted from French maritime pine bark (Pinus maritima), and Proanthodyn, extracted from grape seeds (Vitis vinifera). Talc (talcum powder) increases "ovarian neoplastic transformation" (turns cells of the female ovary into cancerous cells). Q: Can grape seed extract cause digestive problems? Two antioxidants-grape seed and Pycnogenol-are particularly effective at lowering blood pressure, protecting the heart, and improving blood sugar. 1. s (OPCs), are brought to the attention of the CSWG because of widespread consumer use of these substances as dietary supplements. However, Pycnogenol itself should not be confused with formulas that merely contain pycnogenols, as the overall benefits associated with such supplements are not nearly as impressive as those found in proper Pycnogenol. Horse Chestnut Seed Extract vs. Pycnogenol ® for Chronic Venous Insufficiency . Pycnogenol is a patented extract of maritime pine bark, sustainably harvested from trees grown in the South West of France. OPCs are also found in pine bark extracts, such as Pycnogenol . Although both substances have similar actions in the body, they each have some individual recommended medicinal uses. Q: Can you use grape seed extract for dogs? With more than 200 research papers to support its use, Pycnogenol is one of the most studied health supplements. (The more grape seed extract, the lower the blood sugar levels). Learn more about what the research says and how to safely use it. Of couse, you are also correct, it is very expensive . An extract of maritime pine bark called Pycnogenol bears 65-75 percent proanthocyanidins (procyanidins). The benefits of grape seed vitamins include rise in nitric oxide level, just the way Pycnogenol do. With more than 200 research papers to support its use, Pycnogenol is one of the most studied health supplements. Grape seed extract offers complementary properties to Pycnogenol.Ingredients:INGRED If you choose to use Pycnogenol, follow the dosage instructions on the label. Grape seed extract and pine bark extract, including the proprietary products Pycnogenol® (pycnogenol) and Masquelier’s™ Original OPC. Pycnogenol is a patented extract of maritime pine bark, sustainably harvested from trees grown in the South West of France. Grape seed extract offers complementary properties to Pycnogenol. Grape seed extract does seem to work for some people but is variable from one source of grape seed to another. Both resveratrol and grape seed extract are derived from grapes, but unlike grape seed, resveratrol is extracted from grape skins like those used to make red wine. The aim of this study was to compare the efficacy of Venostasin (horse chestnut seed extract) and Pycnogenol (French maritime pine bark extract) in the treatment of chronic venous insufficiency (CVI). Pycnogenol is a patented formulation of Pine Bark Extract which is standardized to 65-75% Procyanidin compounds by weight. Pycnogenol is a popular natural supplement with many uses. caroline2 (Inactive) February 15, 2015 at 2:42 pm If not, two powerful antioxidants offer complementary benefits: grape seed extract and Pycnogenol, a proprietary extract of French maritime pine bark. Pycnogenol is a substance taken from the pine bark of trees found in the southwest region of France. PS: I also own a little book on Grape Seed Extract by Dr. Clark Hansen that I purchased in 1996.....it's my bible on these antioxidants. It's a great little book that gives the history of these supps and all it's uses. Grape seed extract can be applied topically or taken internally, and is the best known source of antioxidants available. Pycnogenol and Grape Seed Extract is a potent combination of two powerful natural antioxidants - Pycnogenol, extracted from French maritime pine bark (Pinus maritima), and Proanthodyn, extracted from grape seeds (Vitis vinifera). While Pycnogenol® is undoubtedly a fine product, its claims to superiority are doubly doubtful as most of this research was done on grape seed extract and then extrapolated to pine bark. Pycnogenol® and Grape Seed Extract is a potent combination of two powerful natural antioxidants - Pycnogenol®, extracted from French maritime pine bark (Pinus maritima), and Proanthodyn™, extracted from grape seeds (Vitis vinifera). Procyanidins are chain-like structures consisted of catechins similar to some found in green tea (the green tea catechins that do not have 'gallate' in their names). *:The extent of the antioxidant potential of pycnogenol in vivo is unclear. Although a balanced level of estrogen is vital to your health, too much estrogen can cause a host of sexual and gender-related problems including… It is standardized to contain 65-75% procyanidins, a class of polyphenols and flavonoids like those found in blueberries, wine, grape skin, citrus, and cocoa . ... Pine bark extract … Grape Seed Extract is an Aromatase Inhibitor Aromatase is an important agent in your body’s chemistry that converts testosterone into estrogen, in humans and other mammals. Anti-Cancer Effects of Grape Seed Extract. Grape seed extract may help delay the development of Alzheimer's disease, according to an animal study published in 2009. Pycnogenol is a patented extract of the French maritime pine bark (Pinus pinaster). A: Both seem to be equally effective, but GSE tends to be more cost-effective. Amounts recommended are 75 mg/day for grape seed extract (or 50 mg/day for children) and for Pycnogenol the amount is 1 mg for each pound of body weight. The proanthocyanidins in grape seed extract are a type of flavonoid naturally found in plants. Pycnogenol is well-known for its effects on wound healing and skin regeneration. Pycnogenol is more regulated than grape seed (pycnogenol is trademarked and all sourced from the same company) and we have found it is generally more active than grape seed. Pycnogenol has several benefits to your health and beauty. Flavonoids , specifically oligomeric procyanidins (OPCs), are present in grape seed extract, and provide extraordinary amounts of antioxidant protection. Pycnogenol is one of the main substances in Pine Bark Extract supplements. This is an incorrect assumption. Research has proven that grape seed extract antibiotic can relax arteries by working on Endothelial Nitric Oxide Synthase (eNOS), which is an enzyme that acts to strengthen the body function. Is your diet chock full of antioxidants? *2004 , James J. Gormley, Shari Lieberman, User's Guide to Brain-Boosting Nutrients , Page 55 *:Masquelier developed a process to extract these compounds — both from pine bark (in 1951) and from grape seeds (1970). Pycnogenol is the registered trademark name for a French formula. Pine bark extract can be found in liquid, tablet or capsule form containing 85 percent to 90 percent OPCs. By Francis Brinker, ND Chronic venous insufficiency (CVI) is a problem of the lower extremities for both youth and adults, affecting 20%-25% of women and 10%-15% of men. In tests on mice, scientists discovered that grape seed extract eased inflammation and prevented the accumulation of substances known to form the brain plaques associated with Alzheimer's disease. If you have a grape seed product that is working for you, I wouldn't suggest changing it for this reason. Pycnogenol is actually a trademarked name for pine bark extract. Cyvex Technologies … Pycnogenol vs. Grape Seed Extract. A: Yes, it has been successfully administered to dogs to prevent blood clots. However, it is also important to see beyond the pyncogenol marketing campaign and understand the … It can also be found as creams, lotions or ointments, typically containing 0.5 percent to 2 percent pine bark extract. ... grape seed, and witch hazel bark. Pycnogenol has also been explored as a remedy for erectile dysfunction due to its effects on nitric oxide levels and blood flow. Grape seed extract may cause minor side effects but has generally been found to be safe, although it may have anticoagulant properties at high doses (Bijak, Nutrients 2019). Both extracts contain proanthocyanidins, a special class of water-soluble bioflavonoids which are excellent free radical scavengers.
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